A1 Journal article (refereed)
Glucose regulation and grip strength in adults : findings from the Helsinki Birth Cohort Study (2021)
Åström, M. J., von Bonsdorff, M. B., Salonen, M. K., Kajantie, E., Osmond, C., & Eriksson, J. G. (2021). Glucose regulation and grip strength in adults : findings from the Helsinki Birth Cohort Study. Archives of Gerontology and Geriatrics, 94, Article 104348. https://doi.org/10.1016/j.archger.2021.104348
JYU authors or editors
Publication details
All authors or editors: Åström, Max J.; von Bonsdorff, Mikaela B.; Salonen, Minna K.; Kajantie, Eero; Osmond, Clive; Eriksson, Johan G.
Journal or series: Archives of Gerontology and Geriatrics
ISSN: 0167-4943
eISSN: 1872-6976
Publication year: 2021
Volume: 94
Article number: 104348
Publisher: Elsevier
Publication country: Ireland
Publication language: English
DOI: https://doi.org/10.1016/j.archger.2021.104348
Publication open access: Openly available
Publication channel open access: Partially open access channel
Publication is parallel published (JYX): https://jyx.jyu.fi/handle/123456789/74017
Abstract
: This study aimed to assess the association between grip strength and glucose regulation in a cross-sectional setting.
Methods
: Using data from the Helsinki Birth Cohort Study, 924 men and 953 women were studied at a mean age of 61.6 years. Grip strength was assessed in the dominant hand using a Newtest Grip Force dynamometer. A standard 2-h 75g oral glucose tolerance test (OGTT) was used to define glucose regulation. The participants were classified into four groups: normoglycaemia, prediabetes (impaired fasting glucose or impaired glucose tolerance), newly diagnosed diabetes and previously known diabetes. The association between grip strength and glucose regulation was assessed using multiple linear regression models.
Results
: Prediabetes was diagnosed in 32.2% and diabetes in 8.4% using the OGTT. A total of 7.8% of the individuals had previously known diabetes. Compared to individuals with normoglycaemia, grip strength was lower for those with newly diagnosed diabetes (-1.8kg, 95% CI -3.2 to -0.5) as well as those with previously known diabetes (-1.8kg, 95% CI -3.2 to -0.4) after adjusting for covariates (age, sex, body mass index, physical activity, education and smoking). No difference in grip strength was found when comparing those with prediabetes and normoglycaemia.
Conclusion
: In adults, grip strength was lower among those with known and newly diagnosed diabetes compared to those with normoglycaemia. Together with previous findings on associations between grip strength and chronic diseases, these results support the use of grip strength as an overall health marker in adults.
Keywords: epidemiology; ageing; diabetes; press force; physical fitness; cohort study
Free keywords: diabetes mellitus; epidemiology; grip strength; physical fitness; prediabetes
Contributing organizations
Ministry reporting: Yes
VIRTA submission year: 2021
JUFO rating: 1
