A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Spectroscopic, density functional theory, nonlinear optical properties and in vitro biological studies of Co(II), Ni(II), and Cu(II) complexes of hydrazide Schiff base derivatives (2021)


Ramadan, R. M., El‐Medani, S. M., Makhlouf, A., Moustafa, H., Afifi, M. A., Haukka, M., & Aziz, A. (2021). Spectroscopic, density functional theory, nonlinear optical properties and in vitro biological studies of Co(II), Ni(II), and Cu(II) complexes of hydrazide Schiff base derivatives. Applied Organometallic Chemistry, 35(7), Article e6246. https://doi.org/10.1002/aoc.6246


JYU-tekijät tai -toimittajat


Julkaisun tiedot

Julkaisun kaikki tekijät tai toimittajatRamadan, Ramadan M.; El‐Medani, Samir M.; Makhlouf, Abdelmoneim; Moustafa, Hussein; Afifi, Manal A.; Haukka, Matti; Aziz, Ayman, Abdel

Lehti tai sarjaApplied Organometallic Chemistry

ISSN0268-2605

eISSN1099-0739

Julkaisuvuosi2021

Ilmestymispäivä29.03.2021

Volyymi35

Lehden numero7

Artikkelinumeroe6246

KustantajaJohn Wiley & Sons

JulkaisumaaBritannia

Julkaisun kielienglanti

DOIhttps://doi.org/10.1002/aoc.6246

Julkaisun avoin saatavuusEi avoin

Julkaisukanavan avoin saatavuus


Tiivistelmä

Complexes of three molecularly designed phenylacetohydrazide Schiff base derivatives—N′‐(2‐hydroxybenzylidene)‐2‐phenylacetohydrazid (HL1), N‐(1‐(2‐hydroxyphenyl)ethylidene)‐2‐phenylacetohydrazide (HL2), and N′‐((1‐hydroxynaphthalen‐2‐yl)methylene)‐2‐phenylacetohydrazide (HL3)—with some bivalent metal ions were synthesized and investigated by several spectroscopic and analytical techniques. The crystal structure of HL1 ligand has been solved by conventional X‐ray diffraction technique. Molecular geometries of HL1 and the studied complexes were investigated using the DFT‐B3LYP/GENECP level of theory. Quantum and non‐quantum global reactivity descriptors as well as the nonlinear optical properties were calculated. Biological parameters such as antimicrobial and antioxidant activities, fluorescence quenching studies, and viscosity measurements of the complexes were carried out. Molecular docking studies of HL1 and complexes using Molecular Operating Environment (MOE) software are reported. The different biological studies and the molecular docking were correlated to each other. The biological studies supported that the complexes can bind to DNA via intercalative mode and showed a various DNA binding potency.


YSO-asiasanatkompleksiyhdisteetkobolttinikkelikupariröntgenkristallografiatiheysfunktionaaliteoriaoptiset ominaisuudetbiologinen aktiivisuus

Vapaat asiasanatbiological activity; CT‐DNA binding; DFT studies; molecular docking; nonlinear optical properties; X‐ray analysis


Liittyvät organisaatiot

JYU-yksiköt:


OKM-raportointiKyllä

Raportointivuosi2021

JUFO-taso1


Viimeisin päivitys 2024-26-03 klo 09:19