A2 Katsausartikkeli tieteellisessä aikausilehdessä
Constructing Large 2D Lattices Out of DNA-Tiles (2021)

Parikka, J. M., Sokołowska, K., Markešević, N., & Toppari, J.J. (2021). Constructing Large 2D Lattices Out of DNA-Tiles. Molecules, 26(6), Article 1502. https://doi.org/10.3390/molecules26061502

JYU-tekijät tai -toimittajat

Julkaisun tiedot

Julkaisun kaikki tekijät tai toimittajat: Parikka, Johannes M.; Sokołowska, Karolina; Markešević, Nemanja; Toppari, J. J.

Lehti tai sarja: Molecules

eISSN: 1420-3049

Julkaisuvuosi: 2021

Volyymi: 26

Lehden numero: 6

Artikkelinumero: 1502

Kustantaja: MDPI

Julkaisumaa: Sveitsi

Julkaisun kieli: englanti

DOI: https://doi.org/10.3390/molecules26061502

Julkaisun avoin saatavuus: Avoimesti saatavilla

Julkaisukanavan avoin saatavuus: Kokonaan avoin julkaisukanava

Julkaisu on rinnakkaistallennettu (JYX): https://jyx.jyu.fi/handle/123456789/75108

Tiivistelmä

The predictable nature of deoxyribonucleic acid (DNA) interactions enables assembly of DNA into almost any arbitrary shape with programmable features of nanometer precision. The recent progress of DNA nanotechnology has allowed production of an even wider gamut of possible shapes with high-yield and error-free assembly processes. Most of these structures are, however, limited in size to a nanometer scale. To overcome this limitation, a plethora of studies has been carried out to form larger structures using DNA assemblies as building blocks or tiles. Therefore, DNA tiles have become one of the most widely used building blocks for engineering large, intricate structures with nanometer precision. To create even larger assemblies with highly organized patterns, scientists have developed a variety of structural design principles and assembly methods. This review first summarizes currently available DNA tile toolboxes and the basic principles of lattice formation and hierarchical self-assembly using DNA tiles. Special emphasis is given to the forces involved in the assembly process in liquid-liquid and at solid-liquid interfaces, and how to master them to reach the optimum balance between the involved interactions for successful self-assembly. In addition, we focus on the recent approaches that have shown great potential for the controlled immobilization and positioning of DNA nanostructures on different surfaces. The ability to position DNA objects in a controllable manner on technologically relevant surfaces is one step forward towards the integration of DNA-based materials into nanoelectronic and sensor devices.

YSO-asiasanat: nanorakenteet; nanotekniikka; DNA

Vapaat asiasanat: DNA self-assembly; DNA origami; DNA nanotechnology; lattice; hierarchy; complexity; lithography

Liittyvät organisaatiot

Hankkeet, joissa julkaisu on tehty

OKM-raportointi: Kyllä

Raportointivuosi: 2021

JUFO-taso: 1