A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Hyperspectral Imaging Reveals Spectral Differences and Can Distinguish Malignant Melanoma from Pigmented Basal Cell Carcinomas : A Pilot Study (2021)
Räsänen, J., Salmivuori, M., Pölönen, I., Grönroos, M., & Neittaanmäki, N. (2021). Hyperspectral Imaging Reveals Spectral Differences and Can Distinguish Malignant Melanoma from Pigmented Basal Cell Carcinomas : A Pilot Study. Acta Dermato-Venereologica, 101(2), Article adv00405. https://doi.org/10.2340/00015555-3755
JYU-tekijät tai -toimittajat
Julkaisun tiedot
Julkaisun kaikki tekijät tai toimittajat: Räsänen, Janne; Salmivuori, Mari; Pölönen, Ilkka; Grönroos, Mari; Neittaanmäki, Noora
Lehti tai sarja: Acta Dermato-Venereologica
ISSN: 0001-5555
eISSN: 1651-2057
Julkaisuvuosi: 2021
Volyymi: 101
Lehden numero: 2
Artikkelinumero: adv00405
Kustantaja: Society for Publication of Acta Dermato-Venereologica
Julkaisumaa: Ruotsi
Julkaisun kieli: englanti
DOI: https://doi.org/10.2340/00015555-3755
Julkaisun avoin saatavuus: Avoimesti saatavilla
Julkaisukanavan avoin saatavuus: Kokonaan avoin julkaisukanava
Julkaisu on rinnakkaistallennettu (JYX): https://jyx.jyu.fi/handle/123456789/75240
Tiivistelmä
Pigmented basal cell carcinomas can be difficult to distinguish from melanocytic tumours. Hyperspectral imaging is a non-invasive imaging technique that measures the reflectance spectra of skin in vivo. The aim of this prospective pilot study was to use a convolutional neural network classifier in hyperspectral images for differential diagnosis between pigmented basal cell carcinomas and melanoma. A total of 26 pigmented lesions (10 pigmented basal cell carcinomas, 12 melanomas in situ, 4 invasive melanomas) were imaged with hyperspectral imaging and excised for histopathological diagnosis. For 2-class classifier (melanocytic tumours vs pigmented basal cell carcinomas) using the majority of the pixels to predict the class of the whole lesion, the results showed a sensitivity of 100% (95% confidence interval 81–100%), specificity of 90% (95% confidence interval 60–98%) and positive predictive value of 94% (95% confidence interval 73–99%). These results indicate that a convolutional neural network classifier can differentiate melanocytic tumours from pigmented basal cell carcinomas in hyperspectral images. Further studies are warranted in order to confirm these preliminary results, using larger samples and multiple tumour types, including all types of melanocytic lesions.
YSO-asiasanat: ihosyöpä; tyvisolusyöpä; diagnostiikka; spektrikuvaus; koneoppiminen; neuroverkot
Vapaat asiasanat: deep learning; neural network; basal cell carcinoma; malignant melanoma
Liittyvät organisaatiot
OKM-raportointi: Kyllä
VIRTA-lähetysvuosi: 2021
JUFO-taso: 2