A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Expansion of rDNA and pericentromere satellite repeats in the genomes of bank voles Myodes glareolus exposed to environmental radionuclides (2021)


Jernfors, T., Danforth, J., Kesäniemi, J., Lavrinienko, A., Tukalenko, E., Fajkus, J., Dvořáčková, M., Mappes, T., & Watts, P. C. (2021). Expansion of rDNA and pericentromere satellite repeats in the genomes of bank voles Myodes glareolus exposed to environmental radionuclides. Ecology and Evolution, 11(13), 8754-8767. https://doi.org/10.1002/ece3.7684


JYU-tekijät tai -toimittajat


Julkaisun tiedot

Julkaisun kaikki tekijät tai toimittajatJernfors, Toni; Danforth, John; Kesäniemi, Jenni; Lavrinienko, Anton; Tukalenko, Eugene; Fajkus, Jiří; Dvořáčková, Martina; Mappes, Tapio; Watts, Phillip C.

Lehti tai sarjaEcology and Evolution

ISSN2045-7758

eISSN2045-7758

Julkaisuvuosi2021

Ilmestymispäivä25.05.2021

Volyymi11

Lehden numero13

Artikkelin sivunumerot8754-8767

KustantajaJohn Wiley & Sons

JulkaisumaaBritannia

Julkaisun kielienglanti

DOIhttps://doi.org/10.1002/ece3.7684

Julkaisun avoin saatavuusAvoimesti saatavilla

Julkaisukanavan avoin saatavuusKokonaan avoin julkaisukanava

Julkaisu on rinnakkaistallennettu (JYX)https://jyx.jyu.fi/handle/123456789/76134


Tiivistelmä

Altered copy number of certain highly repetitive regions of the genome, such as satellite DNA within heterochromatin and ribosomal RNA loci (rDNA), is hypothesized to help safeguard the genome against damage derived from external stressors. We quantified copy number of the 18S rDNA and a pericentromeric satellite DNA (Msat-160) in bank voles (Myodes glareolus) inhabiting the Chernobyl Exclusion Zone (CEZ), an area that is contaminated by radionuclides and where organisms are exposed to elevated levels of ionizing radiation. We found a significant increase in 18S rDNA and Msat-160 content in the genomes of bank voles from contaminated locations within the CEZ compared with animals from uncontaminated locations. Moreover, 18S rDNA and Msat-160 copy number were positively correlated in the genomes of bank voles from uncontaminated, but not in the genomes of animals inhabiting contaminated, areas. These results show the capacity for local-scale geographic variation in genome architecture and are consistent with the genomic safeguard hypothesis. Disruption of cellular processes related to genomic stability appears to be a hallmark effect in bank voles inhabiting areas contaminated by radionuclides.


YSO-asiasanatsäteilybiologiaionisoiva säteilyDNAluonnonvaraiset eläimetmetsämyyräTšernobylin ydinonnettomuus

Vapaat asiasanatanthropogenic disturbance; Chernobyl; copy number; ionizing radiation; Myodes glareolus; rDNA


Liittyvät organisaatiot


Hankkeet, joissa julkaisu on tehty


OKM-raportointiKyllä

Raportointivuosi2021

JUFO-taso1


Viimeisin päivitys 2024-10-03 klo 20:26