A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Corticokinematic coherence is stronger to regular than irregular proprioceptive stimulation of the hand (2021)

Mujunen, T., Nurmi, T., & Piitulainen, H. (2021). Corticokinematic coherence is stronger to regular than irregular proprioceptive stimulation of the hand. Journal of Neurophysiology, 126(2), 550-560. https://doi.org/10.1152/jn.00095.2021

JYU-tekijät tai -toimittajat

Julkaisun tiedot

Julkaisun kaikki tekijät tai toimittajat: Mujunen, Toni; Nurmi, Timo; Piitulainen, Harri

Lehti tai sarja: Journal of Neurophysiology

ISSN: 0022-3077

eISSN: 1522-1598

Julkaisuvuosi: 2021

Ilmestymispäivä: 14.07.2021

Volyymi: 126

Lehden numero: 2

Artikkelin sivunumerot: 550-560

Kustantaja: American Physiological Society

Julkaisumaa: Yhdysvallat (USA)

Julkaisun kieli: englanti

DOI: https://doi.org/10.1152/jn.00095.2021

Julkaisun avoin saatavuus: Avoimesti saatavilla

Julkaisukanavan avoin saatavuus: Osittain avoin julkaisukanava

Julkaisu on rinnakkaistallennettu (JYX): https://jyx.jyu.fi/handle/123456789/77166


Proprioceptive afference can be investigated using corticokinematic coherence (CKC), which indicates coupling between limb kinematics and cortical activity. CKC has been quantified using proprioceptive stimulation (movement actuators) with fixed inter-stimulus interval (ISI). However, it is unclear how regularity of the stimulus sequence (jitter) affects CKC strength. Eighteen healthy volunteers (16 right-handed, 27.8±5.0 yrs, 7 females) participated in magnetoencephalography (MEG) session in which their right-index finger was continuously moved at ~3-Hz with constant 333 ms ISI or with 20% jitter (ISI 333±66 ms) using a pneumatic-movement actuator. Three minutes of data per condition was collected. Finger kinematics were recorded with a 3-axis accelerometer. CKC strength was defined as the peak coherence value in the Rolandic MEG gradiometer pair contralateral to the movement at 3-Hz. Both conditions resulted in significant coherence peaking in the gradiometers over the primary sensorimotor cortex. Constant stimulation yielded stronger CKC at 3 Hz (0.78±0.11 vs. 0.66±0.13, p<0.001) and its first harmonic (0.60±0.19 vs. 0.27±0.11, p<0.001) than irregular stimulation. Similarly, the respective sustained-movement evoked field was also stronger for constant stimulation. The results emphasize the importance of temporal stability of the proprioceptive stimulation sequence when quantifying CKC strength. The weaker CKC during irregular stimulation can be explained with temporal and thus spectral scattering of the paired peripheral and cortical events beyond the mean stimulation frequency. This impairs the signal-to-noise ratio of respective MEG signal and thus CKC strength. When accurately estimating and following changes in CKC strength, we suggest using precise movement actuators with constant stimulation sequence.

YSO-asiasanat: liikeoppi; motoriikka; aivokuori; MEG

Vapaat asiasanat: sensomotoriikka; proprioseptiikka

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OKM-raportointi: Kyllä

Alustava JUFO-taso: 2

Viimeisin päivitys 2022-17-06 klo 10:18