A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Ion mobility mass spectrometry : an efficient tool for the analysis of conformational switch of macrocyclic receptors upon anion binding (2021)


Zimnicka, M., Kalenius, E., Jurczak, J., & Danikiewicz, W. (2021). Ion mobility mass spectrometry : an efficient tool for the analysis of conformational switch of macrocyclic receptors upon anion binding. Analyst, 146(17), 5337-5346. https://doi.org/10.1039/D1AN00958C


JYU-tekijät tai -toimittajat


Julkaisun tiedot

Julkaisun kaikki tekijät tai toimittajatZimnicka, Magdalena; Kalenius, Elina; Jurczak, Janusz; Danikiewicz, Witold

Lehti tai sarjaAnalyst

ISSN0003-2654

eISSN1364-5528

Julkaisuvuosi2021

Volyymi146

Lehden numero17

Artikkelin sivunumerot5337-5346

KustantajaRoyal Society of Chemistry (RSC)

JulkaisumaaBritannia

Julkaisun kielienglanti

DOIhttps://doi.org/10.1039/D1AN00958C

Julkaisun avoin saatavuusEi avoin

Julkaisukanavan avoin saatavuus


Tiivistelmä

Interactions between anions and synthetic macrocyclic receptors belong to the extensively explored area of research due to the particularly important functions of anions in biological and environmental sciences. Structures of anion-macrocycle complexes are closely related to their function, highlighting the importance of structural analysis of the complexes. Here, we discuss the application of ion mobility mass spectrometry (IM-MS) and theoretical calculations to the structural analysis of tetralactam macrocycles (M) with varying flexibility and structural properties, and their complexes with anions [M + X]−. Collision cross section (CCS) values obtained from both direct drift tube (DT) and indirect using traveling-wave (TW) IM-MS measurements supplemented by theoretical calculations were successfully used to describe the structural properties of various macrocycle-anion complexes, proving the suitability of the IM-MS approach for sensitive, selective, and fast detection of anion complexes and characterization of their structures and conformations.


YSO-asiasanatanionitkemialliset sidoksetkompleksiyhdisteetmassaspektrometria


Liittyvät organisaatiot

JYU-yksiköt:


OKM-raportointiKyllä

Raportointivuosi2021

JUFO-taso1


Viimeisin päivitys 2024-03-04 klo 19:56