Lynch Syndrome, lifestyle habits and biomarkers

Laakkonen, Eija; Seppälä, Toni; Mecklin, Jukka-Pekka. (2024). Lynch Syndrome, lifestyle habits and biomarkers. University of Jyväskylä.

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  • Contact person (yes/no)Yes

All authorsLaakkonen, Eija; Seppälä, Toni; Mecklin, Jukka-Pekka

FundersEuropean CommissionPäivikki ja Sakari Sohlberg Foundation



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AvailabilityContact owner

Publication year2024

URN identifier in original repository

DOI identifier in original repository

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DOI identifier in JYX

Description of the dataset

DescriptionThe study, Lynch Syndrome, lifestyle habits and biomarkers, investigates lifestyle habits (physical activity and nutrition) and blood-based biomarkers to understand their associations with cancer risk. The study includes several data types, e.g., self-reported questionnaires and blood samples with further biomarker analysis.

High-throughput sequencing has been done to assess cell-free non-coding RNAs. Nuclear magnetic resonance spectroscopy has been applied to assess circulating metabolomics. Data collection including questionnaires, blood samples and blood sample analytics continues to allow the construction of prospective cancer risk prediction models. Clinical data on cancer status is obtained through Finnish Lynch Syndrome Registry.


Free keywordsmetabolomics
non-coding RNA
Lynch syndrome
Cancer risk prediction
life habits
physical activity

Keywords (YSO)physical activitycancerous diseasesnutritional behaviourmicroRNAbiomarkers

Fields of science3111 Biomedicine315 Sport and fitness sciences318 Medical biotechnology

Follow-up groupsSchool of Wellbeing (University of Jyväskylä JYU) JYU.WellGerontology and Public Health (Faculty of Sport and Health Sciences LTK, SPORT) TGEPhysical activity through life span (University of Jyväskylä JYU) PACTS

Do you deal with data concerning special categories of personal data in your research?Yes

Projects related to dataset

Publications and other outputs related to dataset

Last updated on 2024-04-04 at 14:23