Data from Estrogenic Regulation of Muscle Apoptosis (ERMA) study

Laakkonen, Eija; Kovanen, Vuokko; Sipilä, Sarianna. (2022). Data from Estrogenic Regulation of Muscle Apoptosis (ERMA) study. University of Jyväskylä. https://doi.org/10.17011/jyx/dataset/83491.

All authors: Laakkonen, Eija; Kovanen, Vuokko; Sipilä, Sarianna

Funders: Research Council of Finland; European Commission

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Availability and identifiers

Availability: Contact owner

Publication year: 2022

URN identifier in original repository: http://urn.fi/URN:NBN:fi:jyu-202210074820

DOI identifier in original repository: https://doi.org/10.17011/jyx/dataset/83491

URN identifier in JYX: http://urn.fi/URN:NBN:fi:jyu-202210074820

DOI identifier in JYX: https://doi.org/10.17011/jyx/dataset/83491

Description of the dataset

Description: The multidisciplinary Estrogenic Regulation of Muscle Apoptosis (ERMA) study was designed to reveal how hormonal differences over the menopausal stages affect the physiological and psychological functioning of middle-aged women. In addition, health behaviour (e.g., physical activity and eating behaviour) and blood-based biomarkers are investigated. Biomarker data includes different omics datasets (e.g. metabolomics, genomics, transcriptomics). The complete data set includes baseline data collection and two different follow-ups. The baseline ERMA study (=parent data) is a population-based cohort study, which forms a parent data set for the follow-up studies (ERMA follow-up and EsmiRs). Data set includes 47 to 55 years old Caucasian women living in the city of Jyväskylä or neighboring municipalities in Finland. Population sample was drawn from The Finnish Population Information System (dvv.fi) and is described in Kovanen et al 2018 (doi: 10.1097/GME.0000000000001117). Data collection proceeded in different phases including several questionnaires, biological sampling (blood samples and muscle biopsies for a subset of participants) and laboratory measurements. Physical activity was assessed as self-reports via questionnaires and with accelerometer measurements (ActiGraph). Eating behaviour was assessed through structured questionnaires. Laboratory measurements included body composition measurements (DXA and Inbody), muscle strength (hand grip, knee extension), muscle power (vertical jump test) and paper-pen type of cognition measurements. The English translation of main questionnaire and the study flow indicating connections between baseline ERMA and its follow-ups (by 25.4.2022) are attached.

Language: Finnish; English

Free keywords: women's health, muscle performance, physical activity, eating behaviour, menopausal symptoms, pelvic floor symptoms, blood-based biomarkers

Keywords (YSO): menopause; estrogens; mental well-being; muscle mass; muscle strength; health behaviour

Follow-up groups: Gerontology and Public Health (Faculty of Sport and Health Sciences LTK, SPORT) TGE; School of Wellbeing (University of Jyväskylä JYU) JYU.Well; Physical activity through life span (University of Jyväskylä JYU) PACTS

Profiling area: Physical activity through life span (University of Jyväskylä JYU) PACTS; School of Wellbeing (University of Jyväskylä JYU) JYU.Well

Do you deal with data concerning special categories of personal data in your research?: No

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