HDL as a promoter of the oxygen metabolism (HiPrOxy)
Main funder
Funder's project number: 341058
Funds granted by main funder (€)
- 499 729,00
Funding program
Project timetable
Project start date: 01/09/2021
Project end date: 31/08/2025
Summary
Good aerobic fitness and high circulating high density lipoprotein (HDL) both predict healthy years. Endurance training improves aerobic fitness and increases circulating HDL. Background mechanisms behind association between aerobic fitness and HDL concentration are scarcely known. My aim is to investigate effect of aerobic fitness on composition and function of HDL particles. I also study exercise induced modifications in structure of HDL and cellular level mechanisms through which HDL modulates oxygen metabolism. Results of this study may help to find new targets for treatment of blood vessels or unbalanced metabolism.
Principal Investigator
Primary responsible unit
Follow-up groups
Profiling area: Physical activity through life span (University of Jyväskylä JYU) PACTS
