A1 Journal article (refereed)
Body size at birth and coronary heart disease-related hospital care in adult men : Findings from the Helsinki Birth Cohort Study (2017)

von Bonsdorff, M., von Bonsdorff, M., Martikainen, J., Salonen, M., Kajantie, E., Kautiainen, H., & Eriksson, J. G. (2017). Body size at birth and coronary heart disease-related hospital care in adult men : Findings from the Helsinki Birth Cohort Study. Annals of Medicine, 49(2), 126-133. https://doi.org/10.1080/07853890.2016.1241426

JYU authors or editors

Publication details

All authors or editorsvon Bonsdorff, Monika; von Bonsdorff, Mikaela; Martikainen, Janne; Salonen, Minna; Kajantie, Eero; Kautiainen, Hannu; Eriksson, Johan G.

Journal or seriesAnnals of Medicine



Publication year2017


Issue number2

Pages range126-133

PublisherInforma Healthcare ; Taylor & Francis Group; Finnish Medical Society Duodecim

Place of PublicationAbingdon

Publication countryUnited Kingdom

Publication languageEnglish


Publication open accessNot open

Publication channel open access

Publication is parallel published (JYX)https://jyx.jyu.fi/handle/123456789/52994


Aim: We investigated, among those who had been hospitalized at least once due to coronary heart disease (CHD), the relationship between ponderal index (PI, birthweight/length3) at birth, a measure of thinness, and the age at first hospitalization due to CHD, the number of CHD-related hospital care episodes, and cost of CHD-related hospital care from young adulthood to old age.

Methods and results: Data from the Helsinki Birth Cohort Study included 964 men born in Helsinki, Finland during 1934–1944, who had been hospitalized due to CHD and had birth anthropometrics data. PI (kg/m3) was categorized into low (<25.0), medium (25.0–27.5), and high (>27.5). CHD-related hospital care data were available from 1971 to 2013. We observed an earlier onset of (p = .014 for linearity) and a higher rate of CHD-related hospital care episodes among those in the lowest PI group (incidence rate ratio: 1.35 [95% confidence interval: 1.16–1.59, p < .001]), compared to the highest PI group. CHD-related hospital care costs in the lowest PI group were 25% (p = .001, 4% to 46%) higher compared to those in the highest PI group.

Discussion: Thinness at birth is associated with earlier onset, higher prevalence, and higher accumulated costs of CHD-related hospital in-patient care among men who developed CHD.

Free keywordsage of onset; aging; birthweight; cardiovascular disease; coronary heart disease

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Related projects

Ministry reportingYes

Reporting Year2017

JUFO rating2

Last updated on 2024-10-05 at 23:27