A1 Journal article (refereed)
Physical performance during the menopausal transition and the role of physical activity (2021)

Bondarev, D., Finni, T., Kokko, K., Kujala, U. M., Aukee, P., Kovanen, V., Laakkonen, E. K., & Sipilä, S. (2021). Physical performance during the menopausal transition and the role of physical activity. Journals of Gerontology Series A : Biological Sciences and Medical Sciences, 76(9), 1587-1590. https://doi.org/10.1093/gerona/glaa292

JYU authors or editors

Publication details

All authors or editorsBondarev, Dmitriy; Finni, Taija; Kokko, Katja; Kujala, Urho M; Aukee, Pauliina; Kovanen, Vuokko; Laakkonen, Eija K; Sipilä, Sarianna

Journal or seriesJournals of Gerontology Series A : Biological Sciences and Medical Sciences



Publication year2021

Publication date24/11/2020


Issue number9

Pages range1587-1590

PublisherOxford University Press (OUP)

Publication countryUnited States

Publication languageEnglish


Publication open accessOpenly available

Publication channel open accessPartially open access channel

Publication is parallel published (JYX)https://jyx.jyu.fi/handle/123456789/72820


To examine longitudinal changes in physical performance during the menopausal transition and the role of physical activity (PA) in these changes.
Based on follicle-stimulating hormone levels and bleeding diaries, women (47-55 years) were classified as early (n=89) and late perimenopausal (n=143) and followed prospectively until postmenopausal status, with mean duration of 17.5 and 13.8 months respectively. Physical performance was measured by handgrip force, knee extension torque, vertical jumping height, maximal walking speed and six-minute walking distance. PA was self-reported and categorized as low, medium, high. Longitudinal associations of menopausal status, physical performance and related changes with PA level were analyzed using generalized estimation equations adjusted for duration of hormonal therapy.
A significant decline over the menopausal transition in handgrip force (-2.1%, 95% CI -3.8 to -0.4), knee extension torque (-2.6%, 95% CI -4.5 to -0.8) and vertical jumping height (-2.6%, 95% CI -4.2 to -1.1) and a significant increase in six-minute walking distance (2.1%, 95% CI 1.4 to 2.7) were observed in the total sample. A significant interaction of PA by time was observed in handgrip force and in vertical jumping height. High PA women had greater increase in handgrip strength but greater decline in vertical jumping height than medium, low and inactive women (all p ≤0.001).
Both early and late perimenopausal women show decline in muscle strength and power during the transition to postmenopause. PA seems to influence physical performance during the menopausal transition but understanding the benefits of PA require interventional studies.

Keywordsmenopausephysical fitnessmuscle strengthphysical activitywalking (motion)

Free keywordsmuscle strength; muscle power; walking; menopause; longitudinal changes

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Ministry reportingYes

Reporting Year2021

JUFO rating3

Last updated on 2024-22-04 at 22:31