Individual physical activity profiling in older adults: Reforming the assessment of dose-response relationship (PA-REFORM)
Main funder
Funder's project number: 339391
Funds granted by main funder (€)
- 447 650,00
Funding program
Project timetable
Project start date: 01/09/2021
Project end date: 31/08/2026
Summary
Recent estimates of the prevalence of insufficient physical activity reveal an alarming discrepancy, suggesting that either 20% or 80% of the population are insufficiently active. The problem seems to be the dichotomised classification of physical activity based on an absolute volume, which is especially unsuitable for population groups with functional disabilities, such as older adults. The physical activity guidelines suggest adjusting the level of effort relative to fitness level. Yet, we do not have a method to quantify activity relative to individual fitness. In this project we will suggest novel ways to use data from wearable sensors to examine dose-response relationship between physical activity relative to individual capacity and all-cause mortality.
The baseline data are from a population-based AGNES study for 75, 80 or 85 year old adults, where two wearable sensors recorded free-living movement and electrocardiography simultaneously. In the present study, we will collect follow-up data on physical activity, physical performance and all-cause mortality until seven years after the baseline. This unique longitudinal dataset will advance physical activity assessment in older adults. First, we will calibrate accelerometry and heart rate data to individual physical capacity to provide separate estimates for external and internal load. For this purpose, analysis of heart rate will be regenerated for noisy real-life data utilising novel methodology based on artificial intelligence (deep learning). Finally, dose-response relationship between physical activity and mortality will be assessed using relative instead of absolute volume of activity. The work will redefine physical activity measurement that is in line with the current recommendation through an interdisciplinary collaboration between scientists with expertise in exercise, gerontology, cardiology, physics, and computational science from the Universities of Jyväskylä and Cambridge.
This study will produce a novel method for investigating physical activity relative to individual capacity in older adults. We will enhance measurement of physical activity in scientific research by making our method publicly available and free to use for other research groups. We will enhance heart rate analysis in scientific research and gain new information about the feasibility of heart rate measurement in older cohorts. The study will provide a rationale for updated physical activity guidelines and tools for individual physical activity counselling.
The baseline data are from a population-based AGNES study for 75, 80 or 85 year old adults, where two wearable sensors recorded free-living movement and electrocardiography simultaneously. In the present study, we will collect follow-up data on physical activity, physical performance and all-cause mortality until seven years after the baseline. This unique longitudinal dataset will advance physical activity assessment in older adults. First, we will calibrate accelerometry and heart rate data to individual physical capacity to provide separate estimates for external and internal load. For this purpose, analysis of heart rate will be regenerated for noisy real-life data utilising novel methodology based on artificial intelligence (deep learning). Finally, dose-response relationship between physical activity and mortality will be assessed using relative instead of absolute volume of activity. The work will redefine physical activity measurement that is in line with the current recommendation through an interdisciplinary collaboration between scientists with expertise in exercise, gerontology, cardiology, physics, and computational science from the Universities of Jyväskylä and Cambridge.
This study will produce a novel method for investigating physical activity relative to individual capacity in older adults. We will enhance measurement of physical activity in scientific research by making our method publicly available and free to use for other research groups. We will enhance heart rate analysis in scientific research and gain new information about the feasibility of heart rate measurement in older cohorts. The study will provide a rationale for updated physical activity guidelines and tools for individual physical activity counselling.
Principal Investigator
Other persons related to this project (JYU)
Primary responsible unit
Follow-up groups
Profiling area: Active ageing and care (University of Jyväskylä JYU) AAC; School of Wellbeing (University of Jyväskylä JYU) JYU.Well
Related publications and other outputs
1 of 2
- 24-hour movement behaviors and changes in quality of life over time among community-dwelling older adults : a compositional data analysis (2024) Palmberg, Lotta; et al.; A1; OA
- Comparing the associations between muscle strength, walking speed, and mortality in community-dwelling older adults of two birth cohorts born 28 years apart (2024) Koivunen, Kaisa; et al.; A1; OA
- Free-Living Sit-to-Stand Characteristics as Predictors of Lower Extremity Functional Decline Among Older Adults (2024) Löppönen, Antti; et al.; A1; OA
- Longitudinal changes in life-space mobility and autonomy in participation outdoors among Finnish community-dwelling older adults from pre-COVID-19 to through the pandemic (2024) Lindeman, Katja; et al.; A1; OA
- Physical Activity Changes From Before to During the First Wave of the COVID-19 Pandemic Among Community-Dwelling Older Adults in Finland (2024) Lindeman, Katja; et al.; A1; OA
- Physical Behavior Profiles Among Older Adults and Their Associations With Physical Capacity and Life-Space Mobility (2024) Palmberg, Lotta; et al.; A1; OA
- Reciprocal Associations Between Relative or Absolute Physical Activity, Walking Performance, and Autonomy in Outdoor Mobility Among Older Adults : A 4-Year Follow-Up (2024) Lindeman, Katja; et al.; A1; OA
- The role of cardiorespiratory fitness and body composition in the association between physical activity and menopausal symptoms (2024) Hyvärinen, Matti; et al.; A1; OA
- Association of Sit-to-Stand Capacity and Free-Living Performance Using Thigh-Worn Accelerometers among 60- to 90-Yr-Old Adults (2023) Löppönen, Antti; et al.; A1; OA
- Autonomic nervous system and postural control regulation during orthostatic test as putative markers of physical resilience among community-dwelling older adults (2023) Koivunen, Kaisa; et al.; A1; OA
